Mount Sinai Health System

Department of Environmental Medicine and Public Health Thursday Seminar - Speaker: Sung Kyun Park, Sc.D, MPH “Challenges of PFAS Epidemiologic Research: Reverse Causation and Non-Monotonic Dose-Responses”

Speaker: Sung Kyun Park, Sc.D, MPH, Associate Professor of Epidemiology and Environmental Health Sciences, University of Michigan


Title: Challenges of PFAS Epidemiologic Research: Reverse Causation and Non-Monotonic Dose-Responses

Bio: Dr. Sung Kyun Park is an epidemiologist with research interests in health effects of environmental exposures, with a focus on environmental exposure assessment, epidemiologic causal inference, and the development of analytic approaches to assess multiple pollutant exposures. He is currently PI of two ongoing R01 grants from the NIEHS examining the effects of multi-pollutants on reproductive and metabolic outcomes in midlife women of the Study of Women’s Health Across the Nation (SWAN). 


Abstract: Per- and poly-fluoroalkyl substances (PFAS) are public health concerns because of widespread exposure through contaminated foods/drinking water. These chemicals have recently received enormous attention in the U.S. because of contaminated drinking water. In this talk, Dr. Park will discuss two challenges of PFAS epidemiologic research: First, reverse causation in PFAS and menopausal timing. Previous epidemiologic studies of PFAS and menopausal timing conducted in cross-sectional settings were limited by reverse causation because PFAS serum concentrations increase after menopause. He will show his recent finding in the Study of Women's Health Across the Nation, a prospective cohort study of midlife women. Second, non-monotonic dose-responses. Recent epidemiologic studies have shown 'protective' associations between PFAS and cognition. He will also present preliminary findings of non-linear dose-responses in the association between PFAS and cognitive functions in the US general population (NHANES) and argue against recent publications of protective effects of PFAS.


Date: Thursday, Sept 24, 2020
Time: 12:00pm-1:00pm
Location: CAM Building, 17 E 102nd, 5th Floor West, D5-122


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*Light lunch will be provided. We are trying to be more eco-friendly so please bring your own reusable cup or water bottle.

Thursday, September 24, 2020 at 12:00pm to 1:00pm

CAM Building, 17 E 102nd, 5th Floor West, D5-122, D5-122 CAM Building, 17 E 102nd, 5th Floor West, D5-122