About this Event

One Gustave L. Levy Place New York, NY 10029-6574

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Short Bio:

Dr. Shoshannah Eggers, is an environmental epidemiologist and microbiome researcher. Her research focuses on understanding the role of the human microbiome in mediating the relationship between environmental exposures and downstream health outcomes through the life course. Dr. Eggers completed a BS in Microbiology and PhD in Population Health with a concentration in Epidemiology from the University of Wisconsin-Madison. She went on to do a postdoctoral fellowship at the Icahn School of Medicine at Mount Sinai in the department of Environmental Medicine and Public Health. There, Dr. Eggers received a K99/R00 Pathway to Independence award from the National Institute of Environmental Health Sciences. As an Assistant Professor in Epidemiology at the University of Iowa College of Public Health, Dr. Eggers serves as co-director of the Microbial Exposomics Lab, and an associate member of the Environmental Health Sciences Research Center.

 

Abstract:

In close collaboration with researchers from ISMMS, my lab investigates how prenatal environmental exposures and gut microbiome (GM) composition interact to influence childhood health outcomes. Using data from PROGRESS, a longitudinal birth cohort in Mexico City, we explore the pathways linking prenatal metal exposures to risks for depression and subclinical intestinal inflammation in late childhood. Through advanced statistical and machine-learning techniques, we have identified distinct metal–microbial patterns, or "cliques," associated with these outcomes. Our findings suggest that certain gut microbes, such as Akkermansia muciniphila, may buffer these risks, offering potential avenues for intervention. Additionally, I will discuss reverse translational insights from these studies, shedding light on the biological plausibility of these metal-microbial cliques. This work highlights the importance of understanding how environmental exposures and the GM jointly influence child health and well-being.

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