Mount Sinai Health System

I-HDS and TCI-BSRF Biostatistics Seminar Workshop

I-HDS and TCI-BSRF (Biostatistics Shared Resource Facility) invites you to join its Biostatistics Seminar Workshop being held, Thursday, Feb. 14th at 2:00pm in room 8-101 in the Hess (CSM) Building, 8th Floor. Our featured guest will be Amir Horowitz, PhD, Asst. Prof., Oncological Sciences, ISMMS.

Talk Title: "Harnessing NK cells to improve anti tumor immunity and immunotherapies for hematologic and solid tumor malignancies”


This talk will describe how polymorphisms in HLA-A and HLA-B genes regulate cell-surface expression of HLA-E and how levels of HLA-E expression determine thresholds for immune inhibition and activation that strongly predict prognosis/survivorship in cancer patients as well as predict tumor response/resistance to immunotherapies. The talk will cover some background on Natural Killer cell biology, HLA class I and KIR immunogenetics and clinical data from Dr. Horowitz’s current, unpublished research.


Dr. Amir Horowitz joined the Department of Oncological Sciences and the Precision Immunology Institute and Tisch cancer Institute in May, 2017. He obtained his PhD at the London School of Hygiene & Tropical Medicine in Immunology and Infectious Diseases in London, UK and previously received a BSc from Cornell University in Plant Sciences, plant genetics and pathology. Dr. Horowitz performed his postdoctoral studies at Stanford University on HLA class I and KIR immunogenetics, immunology, structural biology and epidemiology where he studied how HLA class I simultaneously presents antigens to CD8 T cells as well as regulates Natural Killer cell functions.

Thursday, February 14, 2019 at 2:00pm to 3:00pm

Hess Building, 8-101 1470 Madison Avenue, New York, NY 10029

Event Type



Alumni, Faculty, Postdocs, Staff, Students, Health Care Professionals, Prospective Students, Prospective Faculty


Icahn School of Medicine at Mount Sinai


Population Health Science and Policy


The Tisch Cancer Institute



Instructions to join remotely:

Link to WebEx:

Audio through phone: 646-834-9321

Participant Pin Code: 66729341

Meeting Number: 921 579 215


Amir Horowitz, PhD, Asst. Prof., Oncological Sciences, ISMMS.