MDMA restores cortico-accumbal signaling and rescues autism related social deficits

Speaker: 
Jessica Walsh, PhD
Assistant Professor
Department of Pharmacology
University of North Carolina at Chapel Hill

Host: 
Xiaoting (Ting) Wu, PhD
Assistant Professor
Nash Family Department of Neuroscience
Icahn School of Medicine at Mount Sinai

About the Wu lab:
Social cognition is the ability to detect, store, and evaluate social information and it is critical for how we think, feel, and interact with others. Impairment of social cognition is a defining feature of many neuropsychiatric diseases including autism, schizophrenia, and mood disorders. The major goal of our research is to understand the neural mechanisms underlying social cognitive processes such as social perception, social memory, and social decision-making. We are particularly interested in how molecular and neuromodulatory actions shape synaptic properties and circuit function. To achieve this, we combine a variety of approaches across molecular, synaptic, and behavioral scales which include single-cell transcriptomics, ex vivo electrophysiology, in vivo photometric recordings, and optogenetics.

Lab link: https://labs.neuroscience.mssm.edu/project/wu-lab/

Social media:
X: @XiaotingWuLab
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